Kathy Keyvani Selected Research

semapimod

12/2016	The multi-target effects of CNI-1493: convergence of anti-amylodogenic and anti-inflammatory properties in animal models of Alzheimer's disease.
7/2008	CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease.

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Kathy Keyvani Research Topics

Disease

15	Alzheimer Disease (Alzheimer's Disease) 12/2021 - 08/2005
12	Neoplasms (Cancer) 01/2021 - 03/2012
7	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2013
6	Glioma (Gliomas) 04/2021 - 11/2011
4	Brain Neoplasms (Brain Tumor) 01/2020 - 01/2006
4	Amyloid Plaque 02/2016 - 08/2005
3	Cognitive Dysfunction 12/2021 - 08/2009
3	Disease Progression 12/2021 - 02/2016
3	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2006
3	Melanoma (Melanoma, Malignant) 01/2021 - 01/2020
3	Inflammation (Inflammations) 10/2016 - 01/2012
2	Central Nervous System Neoplasms 01/2022 - 03/2012
2	Choroid Plexus Papilloma 12/2021 - 01/2006
2	Multiple Sclerosis 04/2021 - 06/2015
2	Astrocytoma (Pilocytic Astrocytoma) 04/2019 - 11/2011
2	Oligodendroglioma 11/2012 - 11/2011
1	Typical Teratoid Rhabdoid Tumor 01/2022
1	Paresthesia (Dysesthesia) 12/2021
1	Cerebellar Diseases (Cerebellar Syndrome) 01/2021
1	Major Depressive Disorder (Major Depressive Disorders) 07/2020
1	Gliosis 01/2018
1	Neuroinflammatory Diseases 01/2018
1	Central Nervous System Vasculitis 09/2017
1	Psoriasis (Pustulosis Palmaris et Plantaris) 06/2015
1	Mood Disorders (Mood Disorder) 10/2014
1	Necrosis 10/2013
1	Meningioma (Meningiomas) 04/2013
1	Brain Edema (Cerebral Edema) 04/2013
1	AIDS-Related Complex (ARC) 01/2012
1	Memory Disorders (Memory Loss) 08/2009
1	Genetic Predisposition to Disease (Genetic Predisposition) 07/2009
1	Atrophy 07/2008
1	Amyloid angiopathy 08/2006
1	Choroid Plexus Neoplasms (Choroid Plexus Tumor) 01/2006
1	Choroid Plexus Carcinoma 01/2006

Drug/Important Bio-Agent (IBA)

9	Amyloid beta-PeptidesIBA 01/2021 - 08/2005
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2006
4	Peptides (Polypeptides)IBA 02/2016 - 07/2008
4	Amyloid (Amyloid Fibrils)IBA 02/2016 - 08/2005
3	Biomarkers (Surrogate Marker)IBA 12/2021 - 12/2014
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 06/2019 - 12/2014
2	Sirolimus (Rapamycin)FDA Link 01/2021 - 10/2014
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2021
2	Temozolomide (Temodar)FDA LinkGeneric 03/2020 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2020 - 01/2020
2	Methionine (L-Methionine)FDA Link 06/2019 - 03/2019
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018 - 08/2009
2	AntigensIBA 09/2017 - 11/2015
2	semapimodIBA 12/2016 - 07/2008
1	Intravenous Immunoglobulins (IVIG)FDA Link 12/2021
1	RNA (Ribonucleic Acid)IBA 12/2021
1	Tyrosine (L-Tyrosine)FDA Link 04/2021
1	Peptide Hydrolases (Proteases)FDA Link 01/2021
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2021
1	NivolumabIBA 01/2021
1	IpilimumabIBA 01/2021
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 01/2021
1	InterferonsIBA 07/2020
1	Lomustine (CCNU)FDA Link 03/2020
1	LigandsIBA 01/2020
1	NVP-BHG712IBA 01/2020
1	indolamineIBA 01/2020
1	Kallikreins (Kallikrein)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	methionine methyl esterIBA 06/2019
1	N-acetylaspartate (N-acetyl aspartate)IBA 06/2019
1	Choline (Choline Chloride)IBA 06/2019
1	CreatineIBA 06/2019
1	Amino Acids FDA Link 06/2019
1	regorafenibIBA 04/2019
1	Caspase 3 (Caspase-3)IBA 01/2019
1	delta proteinIBA 02/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2017
1	Biological ProductsIBA 02/2016
1	Viral AntigensIBA 11/2015
1	FumaratesIBA 06/2015
1	Pharmaceutical PreparationsIBA 10/2014
1	Keratins (Keratin)IBA 01/2014
1	Aquaporin 5IBA 04/2013
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2013
1	Complementary DNA (cDNA)IBA 11/2012
1	Proteasome Endopeptidase Complex (Proteasome)IBA 03/2012
1	UbiquitinIBA 03/2012
1	3-nitrotyrosineIBA 01/2012
1	SynaptophysinIBA 01/2012
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 11/2011
1	Cyclin-Dependent Kinase Inhibitor p16IBA 11/2011
1	AutoantibodiesIBA 04/2011
1	Levodopa (L Dopa)FDA LinkGeneric 08/2009
1	DNA (Deoxyribonucleic Acid)IBA 01/2006
1	Prealbumin (Transthyretin)IBA 01/2006
1	AntibodiesIBA 01/2006
1	Inwardly Rectifying Potassium Channels (Inward Rectifier Potassium Channels)IBA 01/2006

Therapy/Procedure

10	Therapeutics 01/2021 - 06/2011
1	Artificial Respiration (Mechanical Ventilation) 12/2021
1	Aftercare (After-Treatment) 01/2021
1	Immunotherapy 01/2020
1	Precision Medicine 10/2019
1	Cognitive Training 06/2011